Ascorbic acid activity in adrenal glands of rats with hypervitaminosis A
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چکیده
منابع مشابه
Ascorbic acid activity in adrenal glands of rats with hypervitaminosis A.
Toxic effects of administering large doses of vitamin A have been known for a long time to occur in human beings as well as in laboratory animals (Josephs, 1944; Knudson & Rothman, 1953). Polar bear liver is an unusually potent source of vitamin A and is toxic as a food even for Eskimo's dogs (Rodahl & Moore, 1943). I n hypervitaminosis A basal metabolism is lowered (Sadhu & Brody, 1947) and li...
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1. The effect ofdietary molybdenum on the growth rate and also on ascorbic acid metabolism in rats was studied. An excess of dietary molybdenum resulted in growth retardation and loss of weight. Tolerance to molybdenum was affected by the nature ofthe molybdenum salt administered. 2. Molybdenum ingestion altered certain aspects of ascorbic acid metabolism in rats. The conversion ofD-glucuronola...
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A simple and rapid method has been developed for the determination of ascorbic acid in fruit and pharmaceutical products. The method is based on the measurement of the reaction rate between ammonium molybdate and ascorbic acid in acidic media. The reaction was monitored spectrophotometrically at 800 nm by fixed-time and variable-time methods. The calibration graph was linear in the range of...
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These experiments augment the investigations of adrenal hypertrophy in rats after audiogenic seizures reported by D’Amour and Shaklee (1). Rats were killed after single and repeated audiogenic seizures and the adrenals weighed. Ascorbic acid, cholesterol, and corticosteroids in the adrenals were determined calorimetrically. The data presented indicate that audiogenic seizures are stressful stim...
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It is known that, of all animal species studied, only man, other Primates, and the guinea pig are unable to synthesize ascorbic acid. Results obtained in rats, with radioactive glucose, indicate that ascorbic acid is synthesized by a fairly direct route from glucose (l-3), but no information has been available concerning the rate of synthesis and metabolism of ascorbic acid. Such information wo...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 1965
ISSN: 0007-1145,1475-2662
DOI: 10.1079/bjn19650030